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Scandium(III) Triflate as an Efficient and Reusable Catalyst for Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐ones

✍ Scribed by De, Surya K.; Gibbs, Richard A.


Book ID
127189402
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
97 KB
Volume
35
Category
Article
ISSN
0039-7911

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Silica sulfuric acid efficiently catalyzes the three-component Biginelli reaction between an aldehyde, a b-dicarbonyl compound and urea or thiourea in refluxing ethanol to afford the corresponding dihydropyrimidinones in high yields. The catalyst is reusable and can be applied several times without