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Scandium Triflate Catalyzed Cycloaddition of Imines with 1,1-Cyclopropanediesters: Efficient and Diastereoselective Synthesis of Multisubstituted Pyrrolidines.

โœ Scribed by Yan-Biao Kang; Yong Tang; Xiu-Li Sun


Book ID
101988930
Publisher
John Wiley and Sons
Year
2006
Weight
32 KB
Volume
37
Category
Article
ISSN
0931-7597

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A method to prepare a variety of substituted 3-acyl-5-hydroxybenzofurans efficiently that relies on copper(II) triflate-catalyzed cycloaddition of unactivated 1,4-benzoquinones with 1,3-dicarbonyl compounds is reported. The reaction was shown to be operationally straightforward and proceeds expedien