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Scale-up of controlled-shear affinity filtration using computational fluid dynamics

✍ Scribed by Patrick Francis; Charles A. Haynes


Book ID
112011845
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
303 KB
Volume
4
Category
Article
ISSN
1860-6768

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Controlled shear affinity filtration (CSAF) is a novel integrated processing technology that positions a rotor directly above an affinity membrane chromatography column to permit protein capture and purification directly from cell culture. The conical rotor is intended to provide a uniform and tunab