## Abstract __Penicillium chrysogenum__ was immobilized in polyacrylamide gel prepared from 5% acrylamide monomers (85% acrylamide and 15% __N__,__N__β²βmethylene bisacrylamide). Penicillin produced from glucose by the immobilized mycelium was 17% of that produced by washed mycelium. However, the ac
Scale-down of penicillin production in Penicillium chrysogenum
β Scribed by Lodewijk P. de Jonge; Nicolaas A. A. Buijs; Angela ten Pierick; Amit Deshmukh; Zheng Zhao; Jan A. K. W. Kiel; Joseph J. Heijnen; Dr. Walter M. van Gulik
- Book ID
- 112012361
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 692 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1860-6768
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A previously developed immobilization technique involving latex coatings on solid particulate supports was investigated further for penicillin G production by Penicillium chrysogenum. Several modifications were found to decrease the germination lag time, including a higher spore concentration, a thi