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Scalarane-Based Sesterterpenoid RCE-Protease Inhibitors Isolated from the Indonesian Marine Sponge Carteriospongia foliascens

✍ Scribed by Williams, David E.; Hollander, Irwin; Feldberg, Larry; Frommer, Eileen; Mallon, Robert; Tahir, Akbar; van Soest, Rob; Andersen, Raymond J.

Book ID: 126414625
Publisher: American Chemical Society
Year: 2009
Tongue: English
Weight: 180 KB
Volume: 72
Category: Article
ISSN: 0163-3864
DOI: 10.1021/np900042r

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Novel sesterterpenoid and norsesterterpenoid RCE-protease inhibitors isolated from the marine sponge Hippospongia sp.

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Barangcadoic acid A (1) and rhopaloic acids D (5) to G (8), novel terpenoids with RCE protease inhibitory activity, have been isolated from the marine sponge Hippospongia sp. collected in Indonesia. The structures of 1 and 5-8 were elucidated by analysis of spectroscopic data.