Scalable synthesis of functionalised 2-pyridones via [4+2] cycloaddition reactions of 2-pyrazinones and alkynylboronates
✍ Scribed by Harker, Wesley R.R.; Delaney, Patrick M.; Simms, Michael; Tozer, Matthew J.; Harrity, Joseph P.A.
- Book ID
- 118148287
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 332 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0040-4020
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📜 SIMILAR VOLUMES
## 1. Introduction. the synthetic application of dienamines I [I] as Diels-Alder dienes is well documented'). The main features of their reactions with dienophiles are high reactivity and the fact that the R,N group controls the regiochemistry of the cycloaddition. For example, the use of electron-
## Abstract The reaction of 2(1__H__)‐pyrazinones 1 and 1,2,4‐triazoline‐3,5‐diones 3 was investigated by comparing that of 1 with singlet oxygen. 2(1__H__)‐Pyrazinones 1 reacted in Diels‐Alder fashion with 1,2,4‐triazoline‐3,5‐diones 3 to afford [4+2]‐adducts 4–17 in high yields.