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Scaffold/matrix attachment regions from CHO cell chromosome enhanced the stable transfection efficiency and the expression of transgene in CHO cells

✍ Scribed by Chang, Ming; Liu, Ruijie; Jin, Qingzhe; Liu, Yuanfa; Wang, Xingguo

Book ID
124100861
Publisher
Portland Press
Year
2014
Tongue
English
Weight
739 KB
Volume
61
Category
Article
ISSN
0885-4513

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## Abstract **BACKGROUND:** Transient gene expression (TGE) provides a rapid way to generate recombinant protein biologics for pre‐clinical assessment. Human embryonic kidney (HEK293) cells have traditionally been used for TGE; however, there is demand from industry for efficient, high‐producing TG