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Saxitoxin and procaine act independently on separate sites of the sodium channel

✍ Scribed by H. H. Wagner; W. Ulbricht


Publisher
Springer
Year
1976
Tongue
English
Weight
605 KB
Volume
364
Category
Article
ISSN
0031-6768

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Influence of Na+and Li+ions on the kinet
✍ G. Hansen; W. Ulbricht πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 826 KB

Voltage clamp experiments were done on single myelinated frog nerve fibres. The rate of block of Na + channels by tetrodotoxin (TTX) was obtained from changes in peak Na + current during 1-Hz trains of depolarizing impulses. In hypertonic Na+-rich solution (216 raM) the stationary block was reduced