✦ LIBER ✦
Saturation transfer and chemical exchange measurements of the stereochemical drift occurring during the Wittig reaction
✍ Scribed by Aurelia Pascariu; Mircea Mracec; Stefan Berger
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 234 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0749-1581
- DOI
- 10.1002/mrc.1573
No coin nor oath required. For personal study only.
✦ Synopsis
The Wittig reaction of butylidenetriphenylphosphorane with benzaldehyde using LiHMDS as base in THF was studied. The stereochemical drift (different ratio obtained in alkenes versus oxaphosphetane intermediates) was followed by low-temperature 1D NMR techniques. A retro-Wittig reaction is demonstrated using 13C and 31P saturation transfer experiments and homonuclear DPFGSE-ROE techniques.