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Saturation of intracellular cytosine arabinoside triphosphate accumulation in human leukemic blast cells

✍ Scribed by Gary P. Jamieson; Marie B. Snook; James S. Wiley


Book ID
113239181
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
483 KB
Volume
14
Category
Article
ISSN
0145-2126

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The importance of the cellular pharmacokinetics of cytarabine triphosphate (ara-CTP) with regard to therapeutic efficacy is well established. In vitro and in vivo monitoring of pharmacokinetic parameters of leukemic blast cells were initiated in order to contribute to the pharmacological basis of op