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Sarcoplasmic reticulum Ca2+load in human heart failure

✍ Scribed by Burkert Pieske; Lars S. Maier; Stephan Schmidt-Schweda


Publisher
Springer
Year
2002
Tongue
English
Weight
211 KB
Volume
97
Category
Article
ISSN
0300-8428

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ATPase activity in rat heart sarcoplasmic reticulum was stimulated in a concentration-dependent manner by both Ca 2+ and Mg > in the complete absence of the other cation. Increasing concentrations of Mg 2+ produced an apparent inhibition of the Ca>-dependent ATP hydrolysis. CDTA (trans-l,2-diaminocy