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Sarcoplasmic reticulum Ca 2+ ATPase as a therapeutic target for heart failure

โœ Scribed by Lipskaia, Larissa; Chemaly, Elie R; Hadri, Lahouaria; Lompre, Anne-Marie; Hajjar, Roger J


Book ID
120352262
Publisher
Informa plc
Year
2009
Tongue
English
Weight
902 KB
Volume
10
Category
Article
ISSN
5847-4714

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โœ Rajesh Mahey; Sidney Katz ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer ๐ŸŒ English โš– 574 KB

ATPase activity in rat heart sarcoplasmic reticulum was stimulated in a concentration-dependent manner by both Ca 2+ and Mg > in the complete absence of the other cation. Increasing concentrations of Mg 2+ produced an apparent inhibition of the Ca>-dependent ATP hydrolysis. CDTA (trans-l,2-diaminocy