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Sarcomatoid renal cell carcinoma: basic biology, clinical behavior and response to therapy

✍ Scribed by Debby Chao; Amnon Zisman; Stephen J Freedland; Allan J Pantuck; Jonathan W Said; Arie S Belldegrun


Book ID
117724133
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
217 KB
Volume
6
Category
Article
ISSN
1078-1439

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## Abstract ## BACKGROUND Cyclooxygenase‐2 (COX‐2) plays a major role in the development of cancer through numerous mechanisms. COX‐2 is expressed in the majority of renal cell carcinoma (RCC) tumors and correlates with stage, grade, and microvessel density. Based on potential additive or synergis