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SAR of Sweet Molecules: Conformational Analysis of Two Hypersweet and Two Conformationally Restricted Aspartame Analogues

✍ Scribed by Kamphuis, Johan ;Lelj, Francesco ;Tancredi, Teodorico ;Toniolo, Claudio ;Temussi, Piero A.


Book ID
112185539
Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
695 KB
Volume
11
Category
Article
ISSN
1611-020X

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## Abstract The synthesis and X‐ray diffraction analysis of two dipeptide taste ligands have been carried out as part of our study of the molecular basis of taste. The compounds L‐aspartyl‐D‐α‐methylphenylalanine methyl ester [L‐Asp‐D‐(αMe)Phe‐OMe] and L‐aspartyl‐D‐alanyl‐2,2,5,5‐tetramethylcyclope