## Abstract A 5βHT~3~ receptor agonist based on a benzamide scaffold was identified in a screening of a small commercial compound library, and an elaborate SAR study originating from this hit was performed. The design, synthesis, and functional characterisation of benzamide analogues at the 5βHT~3~
SAR of Psilocybin Analogues: Discovery of a Selective 5-HT2C Agonist.
β Scribed by Howard Sard; Govindaraj Kumaran; Cynthia Morency; Bryan L. Roth; Beth Ann Toth; Ping He; Louis Shuster
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 14 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
LY301317 ((4r)-(-)-4-(dipropylamino)-6-(5-oxazolinyl)-1, 3,4,5-tetrahydrobenz[c,d]indole) has high affinity for the 5-HT 1A receptor and weak affinity for the 5-HT 1D and histamine-H 1 receptors. No significant affinity was found for the other amine receptors studied. In rats, LY301317 produced pote