Sanguinarine inhibits osteoclast formation and bone resorption via suppressing RANKL-induced activation of NF-κB and ERK signaling pathways
✍ Scribed by Li, Haowei; Zhai, Zanjing; Liu, Guangwang; Tang, Tingting; Lin, Zhen; Zheng, Minghao; Qin, An; Dai, Kerong
- Book ID
- 123267370
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 820 KB
- Volume
- 430
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Receptor activator NF‐κB ligand (RANKL)‐activated signaling is essential for osteoclast differentiation, activation and survival. Caffeic acid phenethyl ester (CAPE), a natural NF‐κB inhibitor from honeybee propolis has been shown to have anti‐tumor and anti‐inflammatory properties. In
## Abstract Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast