Samarium(II)-mediated 4-exo trig ketyl-o
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Derek Johnston; Catherine M. McCusker; David J. Procter
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Article
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1999
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Elsevier Science
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French
โ 259 KB
7,5-Unsaturated aldehydes having a quaternary centre in either the ct or ~-position, have been prepared from substituted y-butyrolactones and undergo efficient 4-exo-trig ketyl-olefin cyclisation on treatment with samarium(II) iodide to give functionalised cyclobutanols. In all cases cyclisation occ