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Salvianolic acid B suppresses IFN-γ-induced JAK/STAT1 activation in endothelial cells

✍ Scribed by Shih Chung Chen; Yun Lian Lin; Bin Huang; Danny Ling Wang; Jing Jy Cheng

Book ID
116914859
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
551 KB
Volume
128
Category
Article
ISSN
0049-3848

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## Abstract We report here a role for cyclic AMP‐responsive element‐binding protein‐1 (CREB‐1) in B cell antigen receptor (BCR)‐induced growth inhibition by IFN‐γ. BCR‐induced proliferation is negatively regulated by IFN‐γ. Stimulation through BCR resulted in dose‐dependent induction of CREB‐1 bind