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Salvianolic acid A, a polyphenolic derivative fromSalvia miltiorrhizabunge, as a multifunctional agent for the treatment of Alzheimer’s disease

✍ Scribed by Ying Ying Cao, Ling Wang, Hu Ge, Xi Lin Lu, Zhong Pei, Qiong Gu…

Book ID: 120750568
Publisher: Springer
Year: 2013
Tongue: English
Weight: 875 KB
Volume: 17
Category: Article
ISSN: 1381-1991
DOI: 10.1007/s11030-013-9452-z

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## Abstract Finding inhibitors of the first step of the amyloid cascade, Aβ~42~ generation, is a major goal of Alzheimer's disease drug development. Two target protease activities, β‐and γ‐secretase, were detected more than 10 years ago but progress in this area has been slow because the enzymes we