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Salvage chemotherapy for patients with germ cell tumors. The memorial sloan-kettering cancer center experience (1979–1989)

✍ Scribed by Robert J. Motzer; Nancy L. Geller; Claire C.-Y. Tan; Harry Herr; Michael Morse; William Fair; Joel Sheinfeld; Pramod Sogani; Paul Russo; George J. Bosl

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 542 KB
Volume: 67
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19910301)67:5<1305::aid-cncr2820670506>3.0.co;2-j

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Although the majority of patients with poor-risk germ-cell tumors (GCTs) will achieve a durable complete remission (CR) with standard first-line therapy, 20% to 30% of them will either relapse or fail to achieve an initial CR and eventually die. For this reason, the strategy of using high-dose (HD)