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Salts of the anti-HIV drug lamivudine with phthalic and salicylic acids

✍ Scribed by Capeletti da Silva, Cameron; Coelho, Renan Rezende; de Lima Cirqueira, Marilia; Campos de Melo, Ariane Carla; Landre Rosa, Iara Maria; Ellena, Javier; Martins, Felipe Terra

Book ID
120155670
Publisher
Royal Society of Chemistry
Year
2012
Tongue
English
Weight
860 KB
Volume
14
Category
Article
ISSN
1466-8033

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πŸ“œ SIMILAR VOLUMES

Drug biotransformation interactions in m
Drug biotransformation interactions in man II: A pharmacokinetic study of the simultaneous conjugation of Benzoic and Salicylic Acids with Glycine
✍ Lewis P. Amsel; Gerhard Levy πŸ“‚ Article πŸ“… 1969 πŸ› John Wiley and Sons 🌐 English βš– 587 KB

The major route of biotransformation of benzoic acid and salicylic acid in man is conjugation with glycine, resulting in the formation of hippuric acid and salicyluric acid, respectively. Both processes are capacity-limited in the usual dose range and approach a maximum rate following administration