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Salts of quinidine with pyridinecarboxylic acids

✍ Scribed by Karl Schoen

Book ID
118841741
Publisher
Elsevier Science
Year
1957
Tongue
English
Weight
167 KB
Volume
69
Category
Article
ISSN
0003-9861

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πŸ“œ SIMILAR VOLUMES

Directed lithiation of unprotected pyrid
Directed lithiation of unprotected pyridinecarboxylic acids
✍ Florence Mongin; FranΓ§ois TrΓ©court; Guy QuΓ©guiner πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 229 KB

The lithium salts of 2-, 3-and 4-pyridinecarboxylic acids undergo deprotonation at the position adjacent to the carboxylate group when treated with LTMP in THF at 0 Β°C, -50 Β°C and -25 Β°C, respectively. The lithiation conditions could be extended to chloronieotinic acids, and even to an activated ben