Salivary gland carcinomas in children: A review of 15 cases

✍ Scribed by Taylor, Roger E. ;Gattamaneni, H. Rao ;Spooner, David

• Publisher: John Wiley and Sons
• Year: 1993
• Tongue: English
• Weight: 354 KB
• Volume: 21
• Category: Article
• ISSN: 0098-1532
• DOI: 10.1002/mpo.2950210607

✦ Synopsis

Abstract

Salivary gland carcinomas are rare in childhood. We have reviewed the case records of 15 children aged 3–14 years (median 11) identified from children's tumour registries. Primary sites were parotid: 11, submandibular: 3, and base of tongue: 1. The range of histologies was similar to that occurring in adults. Six were treated by complete excision, with one given post‐operative radiotherapy (RT). All six remain disease‐free at 2 months to 21 years after completion of treatment. Five were treated by partial or sub‐total excision. Four were given post‐operative RT, of whom 3 are disease‐free at 3 years, 6 months ‐ 18 years and 1 lost to follow‐up (LTFA). One not given RT developed a local recurrence at 11 months and was given RT and LTFA. Four patients had a biopsy only. Three were treated by RT. One is disease‐free at 8 years, one died of metastatic disease at 6 months, and one developed a local recurrence at 11 years and has remained disease‐free following salvage surgery. One patient with advanced disease not suitable for RT died 3 months after diagnosis. Complete excision is the treatment of choice. Following sub‐total or incomplete excision post‐operative RT can prevent recurrence. Careful RT planning is necessary to minimise late effects. © 1993 Wiley‐Liss, Inc.