Salicifoline and salicinolide, new diterpene polyesters from Euphorbia salicifolia
✍ Scribed by Judit Hohmann; Ferenc Evanics; György Dombi; Pál Szabó
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 79 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Two new diterpenes (1 and 2) were isolated from a dichloromethane extract of fresh, whole plants of Euphorbia salicifolia: salicifoline (1) is the first representative of a new type of tricyclic diterpenes involving a novel 5-8-8 fused ring system, and salicinolide ( 2) is a bishomoditerpene lactone based on the jatrophane skeleton. The carbon skeleton of 1 is formally derived from jatrophane via transannular intramolecular C C bond formation between C-12 and C-17.
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AbstractÐTwo new diterpene polyesters, serrulatin A (1) and B (2), were isolated from an n-hexane extract of the whole, undried plant of Euphorbia serrulata. The structures were elucidated by various spectroscopic methods, including ESI-MS, IR, UV, 1D and 2D NMR techniques and X-ray crystallography.