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Salbutamol-induced airway hyperreactivity in guinea pigs is not due to a loss of its bronchodilator effect

โœ Scribed by Karl-Heinz Buchheit; Alfred Hofmann; John R. Fozard


Book ID
115890595
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
323 KB
Volume
287
Category
Article
ISSN
0014-2999

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โœ M. Kurosawa; H. Tsukagoshi ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Elsevier ๐ŸŒ English โš– 350 KB

SUMMARY: We studied the effect of iv administration of leukotriene (LT) \(\mathrm{C}_{4}\) on bronchial responsiveness to histamine and airway wall thickening in guinea-pigs. The infusion of \(3 \mu \mathrm{g} / \mathrm{kg} \mathrm{LTC}\) for \(1 \mathrm{~h}\) induced an increase of the relative thi