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Sal-like protein 4: an epithelial and germ cell marker

✍ Scribed by Jain, Deepali


Book ID
122649066
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
62 KB
Volume
44
Category
Article
ISSN
1532-8392

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## Abstract Pregnancy‐Associated Plasma Protein‐A (PAPP‐A) proteolyses insulin‐like growth factor binding protein‐4 (IGFBP‐4), thereby regulating local IGF availability. Reduced PAPP‐A mRNA expression has been reported in ovarian cancer specimens compared to normal ovarian surface epithelial cells