The renal clearance of disopyramide afte
โ
J. R. Lawrence; S. M. Bryson; D. J. Sumner; B. C. Campbell; B. Whiting
๐
Article
๐
1979
๐
John Wiley and Sons
๐
English
โ 306 KB
## Abstract Following bolus intravenous injection of disopyramide in eight normal volunteers the renal clearance of the drug appeared to fall with time. In the first two hours after injection renal clearance had a mean value of 89ยท0 ml min^โ1^ and fell to 29ยท4 ml min^โ1^ between 48 and 72 h. In a