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Safety and Efficacy of Teduglutide After 52 Weeks of Treatment in Patients With Short Bowel Intestinal Failure

✍ Scribed by O'Keefe, Stephen J.D.; Jeppesen, Palle B.; Gilroy, Richard; Pertkiewicz, Marek; Allard, Johane P.; Messing, Bernard


Book ID
122930818
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
859 KB
Volume
11
Category
Article
ISSN
1542-3565

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## Abstract Phenylketonuria (PKU) is an inherited metabolic disease characterized by phenylalanine (Phe) accumulation, which can lead to neurocognitive and neuromotor impairment. Sapropterin dihydrochloride, an FDA‐approved synthetic formulation of tetrahydrobiopterin (6R‐BH4, herein referred to as