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Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

✍ Scribed by Coelho, Teresa; Adams, David; Silva, Ana; Lozeron, Pierre; Hawkins, Philip N.; Mant, Timothy; Perez, Javier; Chiesa, Joseph; Warrington, Steve; Tranter, Elizabeth; Munisamy, Malathy; Falzone, Rick; Harrop, Jamie; Cehelsky, Jeffrey; Bettencourt, Brian R.; Geissler, Mary; Butler, James S.; Sehgal, Alfica; Meyers, Rachel E.; Chen, Qingmin; Borland, Todd; Hutabarat, Renta M.; Clausen, Valerie A.; Alvarez, Rene; Fitzgerald, Kevin; Gamba-Vitalo, Christina; Nochur, Saraswathy V.; Vaishnaw, Akshay K.; Sah, Dinah W.Y.; Gollob, Jared A.; Suhr, Ole B.

Book ID
120927585
Publisher
Massachusetts Medical Society
Year
2013
Tongue
English
Weight
680 KB
Volume
369
Category
Article
ISSN
0096-6762

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Familial amyloidotic polyneuropathy is the common form of hereditary generalized amyloidosis and is characterized by the accumulation of amyloid fibrils in the peripheral nerves and other organs. Liver transplantation (LTx) has been utilized as a therapy for familial amyloidotic polyneuropathy becau