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Safety and efficacy of rituximab in systemic lupus erythematosus: Results from 136 patients from the French autoimmunity and rituximab registry

✍ Scribed by Benjamin Terrier; Zahir Amoura; Philippe Ravaud; Eric Hachulla; Romain Jouenne; Bernard Combe; Christine Bonnet; Patrice Cacoub; Alain Cantagrel; Michel De Bandt; Olivier Fain; Bruno Fautrel; Philippe Gaudin; Bertrand Godeau; Jean-Robert Harlé; Arnaud Hot; Jean-Emmanuel Kahn; Olivier Lambotte; Claire Larroche; Jean Léone; Olivier Meyer; Béatrice Pallot-Prades; Edouard Pertuiset; Pierre Quartier; Thierry Schaerverbeke; Jean Sibilia; Alexandre Somogyi; Martin Soubrier; Eric Vignon; Brigitte Bader-Meunier; Xavier Mariette; Jacques-Eric Gottenberg


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
157 KB
Volume
62
Category
Article
ISSN
0004-3591

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## Abstract ## Objective B cells are likely to contribute to the pathogenesis of systemic lupus erythematosus (SLE), and rituximab induces depletion of B cells. The Exploratory Phase II/III SLE Evaluation of Rituximab (EXPLORER) trial tested the efficacy and safety of rituximab versus placebo in p