Safety and efficacy of rituximab in systemic lupus erythematosus: Results from 136 patients from the French autoimmunity and rituximab registry
✍ Scribed by Benjamin Terrier; Zahir Amoura; Philippe Ravaud; Eric Hachulla; Romain Jouenne; Bernard Combe; Christine Bonnet; Patrice Cacoub; Alain Cantagrel; Michel De Bandt; Olivier Fain; Bruno Fautrel; Philippe Gaudin; Bertrand Godeau; Jean-Robert Harlé; Arnaud Hot; Jean-Emmanuel Kahn; Olivier Lambotte; Claire Larroche; Jean Léone; Olivier Meyer; Béatrice Pallot-Prades; Edouard Pertuiset; Pierre Quartier; Thierry Schaerverbeke; Jean Sibilia; Alexandre Somogyi; Martin Soubrier; Eric Vignon; Brigitte Bader-Meunier; Xavier Mariette; Jacques-Eric Gottenberg
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 157 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective B cells are likely to contribute to the pathogenesis of systemic lupus erythematosus (SLE), and rituximab induces depletion of B cells. The Exploratory Phase II/III SLE Evaluation of Rituximab (EXPLORER) trial tested the efficacy and safety of rituximab versus placebo in p