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Safety and Efficacy of Oxaliplatin and Fluoropyrimidine Regimens With or Without Bevacizumab As First-Line Treatment of Metastatic Colorectal Cancer: Results of the TREE Study

✍ Scribed by Hochster, H. S.; Hart, L. L.; Ramanathan, R. K.; Childs, B. H.; Hainsworth, J. D.; Cohn, A. L.; Wong, L.; Fehrenbacher, L.; Abubakr, Y.; Saif, M. W.; Schwartzberg, L.; Hedrick, E.


Book ID
126716625
Publisher
American Society of Clinical Oncology
Year
2008
Tongue
English
Weight
149 KB
Volume
26
Category
Article
ISSN
0732-183X

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## Purpose This randomized study assessed whether the best overall response rate (ORR) of cetuximab combined with oxaliplatin, leucovorin, and fluorouracil (FOLFOX-4) was superior to that of FOLFOX-4 alone as first-line treatment for metastatic colorectal cancer. The influence of KRAS mutation sta