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Safety and efficacy of atovaquone and proguanil hydrochloride for the prophylaxis of Plasmodium falciparum Malaria in South Africa

โœ Scribed by J. Dirk van der Berg; Cornelia S.J. Duvenage; Neil S. Roskell; Trevor R. Scott

Book ID
117321027
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
653 KB
Volume
21
Category
Article
ISSN
0149-2918

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Efficacy and pharmacokinetics of atovaqu
Efficacy and pharmacokinetics of atovaquone and proguanil in children with multidrug-resistant Plasmodium falciparum malaria
โœ A. Sabchareon; P. Attanath; P. Phanuaksook; P. Chanthavanich; Y. Poonpanich; D. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 899 KB

A trial was conducted in 32 Thai children with uncomplicated multidrug-resistant falciparum malaria to assess the efficacy, safety and pharmacokinetics of atovaquone and proguanil; plasma concentrations of atovaquone, proguanil and its metabolite, cycloguanil, were measured in a subset of 9 children