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Saccharide Sensing Based on Saccharide-Induced Conformational Changes in Fluorescent Boronic Acid Polymers

✍ Scribed by Yasumasa Kanekiyo; Hiroaki Sato; Hiroaki Tao


Publisher
John Wiley and Sons
Year
2005
Tongue
English
Weight
112 KB
Volume
26
Category
Article
ISSN
1022-1336

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✦ Synopsis


Abstract

Summary: A novel fluorometric saccharide detection strategy has been established by utilizing saccharide‐induced conformational changes in copolymers containing boronic acid and fluorescent units. The polymer chain changes its conformation due to an alteration of the charge state induced by binding with saccharides. The conformational changes are conveniently detected by monitoring excimer to monomer intensity ratio in the fluorescence spectra. Thus, the present strategy would be a promising way for the creation of highly selective and sensitive saccharide‐sensing systems.

Saccharide‐induced conformational change in copolymers containing boronic acid units.

magnified imageSaccharide‐induced conformational change in copolymers containing boronic acid units.


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