Saccadic impairments in Huntington’s disease
✍ Scribed by A. Peltsch; A. Hoffman; I. Armstrong; G. Pari; D. P. Munoz
- Book ID
- 105907827
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 523 KB
- Volume
- 186
- Category
- Article
- ISSN
- 0014-4819
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## Abstract The purpose of this study was to quantify gait impairments in presymptomatic and symptomatic Huntington's disease (HD) subjects, and examine sensitivity of gait measures. Our sample (n = 65) included presymptomatic mutation carriers (PMC) (n = 15), symptomatic HD subjects (SHD) (n = 30)
## Abstract ## Background: Huntington's disease (HD) is an autosomal dominant degenerative brain disorder that is characterized by motor, cognitive, and affective symptoms. There is, to some, degree, phenomenological overlap with schizophrenia. Schizophrenia patients are frequently impaired in “th
Clinical rating, caudate atrophy, disturbed movement performance, neuropsychological testing, and age-related genetic disease load (CAG index) are tools that reflect impairment after onset of Huntington's disease (HD). Objectives were to compare scored HD symptoms, results of neuropsychological test