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Sa1918 Better off Naïve: Predictors of Adalimumab Dose Escalation in Patients With Crohn's Disease

✍ Scribed by Moncrief, Karli; Steinhart, A. Hillary; Croitoru, Ken; Newman, Alvin; Nguyen, Geoffrey C.; Xu, Wei; Silverberg, Mark S.


Book ID
122126623
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
122 KB
Volume
142
Category
Article
ISSN
0016-5085

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Predictors of adalimumab dose escalation
✍ Russell D. Cohen; Jeffrey R. Lewis; Hannah Turner; Laura E. Harrell; Stephen B. 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 167 KB 👁 2 views

Background: Pivotal trials for adalimumab (ADA) demonstrated effectiveness versus placebo for induction and maintenance of remission in moderate to severely active Crohn's disease (CD). Although the approved maintenance regimen in the U.S. is 40 mg subcutaneously every 14 days, some patients require