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Sa1713 Targeting Pancreatic Cancer Stroma by HDAC Inhibitors

✍ Scribed by Ghallab, Mohammed; Rosignoli, Guglielmo; Escrig, Irene S.; Bhattacharya, Satya; Kocher, Hemant

Book ID
123542045
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
700 KB
Volume
144
Category
Article
ISSN
0016-5085

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## Abstract The histone deacetylases (HDACs) are able to regulate gene expression, and inhibitors of the HDACs (HDACIs) hold promise in the treatment of cancer as well as a variety of neurodegenerative diseases. To investigate the potential for isoform selectivity in the inhibition of HDACs, we pre