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Sa1262 The Impact of Thiopurine Hypermethylation on Clinical Outcomes in Patients With Inflammatory Bowel Disease

✍ Scribed by Blaker, Paul A.; Fong, Steven C.; Smith, Melissa A.; Kariyawasam, Viraj C.; Marinaki, Anthony M.; Irving, Peter M.; van Sanderso, Jeremy D.


Book ID
122206538
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
49 KB
Volume
146
Category
Article
ISSN
0016-5085

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Background: Circulating concentrations of 6-thioguanine nucleotide (6-TGN) and 6-methyl mercaptopurine (6-MMP) are associated with thiopurine efficacy and may predict toxicity. This study aimed to examine retrospectively the utility of measuring metabolite concentrations in patients with inflammator