Genetic alterations as clonal markers fo
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Li Mao
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Article
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1996
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John Wiley and Sons
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English
โ 551 KB
Bladder cancer i s the result of a clonal expansion of cancer cells in which multiple genetic alterations have accumulated. Point mutations of the p53 gene are frequently observed in bladder cancer. Loss of a retinoblastoma (Rb) allele is also common in bladder cancer. Recent data have shown frequen