S27.5: Two-Stage Genotyping in Association Studies incorporating Linkage Disequilibrium between Markers

On selecting markers for association stu

On selecting markers for association studies: Patterns of linkage disequilibrium between two and three diallelic loci

✍ Chad Garner; Montgomery Slatkin 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 182 KB

## Abstract Association studies depend on linkage disequilibrium (LD) between a causative mutation and linked marker loci. Selecting markers that give the best chance of showing useful levels of LD with the causative mutation will increase the chances of successfully detecting an association. This