## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
S.21.03 Dopamine D4 receptor antagonists, schizophrenia and beyond?
β Scribed by Smita Patel
- Book ID
- 118599718
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 300 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0924-977X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The identification of a novel dopamine receptor subtype, referred to as the D4 receptor, which binds the atypical antipsychotic drug clozapine with high potency, has led to the initiation of a drug discovery program that aims to find novel inhibitors of this receptor subtype. A selective screening s
The dopamine D4 receptor is of major interest in schizophrenia research due to its high affinity for the atypical neuroleptic clozapine and a high degree of variability in the receptor gene (DRD4). Although several genetic linkage analyses performed on schizophrenia multiplex families from different