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S21 GSK3-β A potent regulator of toll-like receptor-mediated inflammation in inflammatory bowel disease

✍ Scribed by C. Hofmann; N. Dunger; J. Schoelmerich; W. Falk; F. Obermeier


Book ID
119637678
Publisher
Oxford University Press
Year
2010
Weight
42 KB
Volume
4
Category
Article
ISSN
1873-9954

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Glycogen synthase kinase 3-β: A master r
✍ Claudia Hofmann; Nadja Dunger; Jürgen Schölmerich; Werner Falk; Florian Obermeie 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 549 KB

Background: A disturbed regulation of Toll-like receptor (TLR) signal transduction resulting in the exclusive activation of proinflammatory signaling pathways may be critical for the perpetuation of established chronic colitis. Glycogen synthase kinase 3-b (GSK3-b) was recently identified as an impo