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S2053 A New Method for Detection and Monitoring of Colonic Carcinogenesis and Angiogenesis in a Novel Mouse Model

✍ Scribed by Becker, Valentin; Greten, Florian; Kerle, Irina; Schmid, Roland M.; Meining, Alexander

Book ID
123437549
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
239 KB
Volume
136
Category
Article
ISSN
0016-5085

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## Abstract A novel heterocyclic amine, 9‐(4′‐aminophenyl)‐9__H__‐pyrido[3,4‐__b__]indole (aminophenylnorharman, APNH), which is formed from nonmutagenic 9__H__‐pyrido[3,4‐__b__]indole (norharman) and aniline, is mutagenic to bacteria and mammalian cells and potently carcinogenic in rats. APNH is d