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S1999 Different Genetic and Epigenetic Signatures in Nodal and Liver Metastases of Colorectal Cancer

✍ Scribed by Miranda, Elena; Balladore, Emanuela; Baryshnikova, Ekaterina; Bianchi, Paolo; Morenghi, Emanuela; Destro, Annarita; Malesci, Alberto; Laghi, Luigi; Roncalli, Massimo

Book ID: 123266933
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 71 KB
Volume: 136
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(09)61415-3

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## Abstract The majority of genetic studies of colorectal carcinogenesis have focused on changes found in primary tumors. Despite the fact that liver metastases are a leading cause of colorectal cancer deaths, the molecular genetic basis of the advanced disease stages remains poorly understood. We