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S1933 Identification of Novel Methylated Genes in Barrett's Esophagus With High-Grade Dysplasia and Esophageal Adenocarcinoma Using Methylation Arrays

✍ Scribed by Kaz, Andrew; Dzieciatkowski, Slavomir; Upton, Melissa P.; Chak, Amitabh; Willis, Joseph; Grady, William M.


Book ID
123247211
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
46 KB
Volume
138
Category
Article
ISSN
0016-5085

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## Abstract Hypermethylation of secreted frizzled‐related proteins (__SFRP__) genes frequently occurs with several cancers but has not been studied in esophageal adenocarcinoma or its precursorβ€”Barrett's esophagus. To explore the role of __SFRP__ methylation in the neoplastic progression of Barrett