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S1699 DKK-1, a Secreted Wnt Antagonist, Activates the WNT5A Receptor, Ror2, to Stimulate Non-Canonical Wnt Signaling in the Intestine

โœ Scribed by Kelly, Jacqueline; Jantz, Jay; Luco, Stephanie; MacLeod, R. John


Book ID
123236951
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
49 KB
Volume
138
Category
Article
ISSN
0016-5085

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The receptor tyrosine kinase Ror2 is inv
โœ Isao Oishi; Hiroaki Suzuki; Nobuyuki Onishi; Ritsuko Takada; Shuichi Kani; Bisei ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 290 KB

## Abstract **Background:** Ror2 is an orphan receptor, belonging to the Ror family of receptor tyrosine kinases. Although Ror2 has been shown to play crucial roles in developmental morphogenesis, the precise signalling events that Ror2 mediates remain elusive. Since Ror2 possesses an extracellular