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S1622 Calcium Transients Activate the Cyclin-Dependent P34cdc2 Kinase Via Calmodulin Resulting in Stabilization/Accumulation of the Anti-Apoptosis Protein, Survivin, That Mediates Cytoprotection Against Ethanol-Induced Gastric Mucosal Injury

✍ Scribed by Jones, Michael K.; Padilla, Oscar R.

Book ID
122376862
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
75 KB
Volume
134
Category
Article
ISSN
0016-5085

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The anti-apoptosis protein, survivin, me
The anti-apoptosis protein, survivin, mediates gastric epithelial cell cytoprotection against ethanol-induced injury via activation of the p34cdc2 cyclin-dependent kinase
✍ Michael K. Jones; Oscar R. Padilla; Nicole A. Webb; Manith Norng 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 685 KB

## Abstract The anti‐apoptosis protein, survivin, promotes cell survival and mitosis. Recent studies have demonstrated that survivin is expressed in normal gastric mucosa. Using an in vitro model, we examined whether survivin plays a role in the cytoprotection produced in gastric mucosa by mild irr