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S1572 Epimorphin Protects Hepatocytes from Oxidative Stress By Inhibiting Mitochondrial Injury

✍ Scribed by Kinoshita, Nobukatsu; Horie, Yasuo; Ohshima, Shigetoshi; Dohmen, Takahiro; Jin, Mario; Ohnishi, Hirohide


Book ID
123597565
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
61 KB
Volume
136
Category
Article
ISSN
0016-5085

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Isolated hepatocykes, suspended in an organ preservation solution, can be preserved at 4" C for up to 6 days. After preservation, normothermic-normoxic incubation causes loss of hepatocyte viability. The addition of 3 mmol/L glycine to the rewarming medium prevents the loss of viability. In this stu