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S1248 The Relationship Between Azathioprine / 6-Mercaptoputine Dose and 6-Thioguanine Nucleotide Levels in Children with Inflammatory Bowel Diseases

✍ Scribed by Yoram Bujanover; Arie Levine; Reuven Bromberg; Akiva Fradkin; Batya Weiss


Book ID
119428841
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
68 KB
Volume
134
Category
Article
ISSN
0016-5085

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## Background: 6-thioguanine nucleotides (6-tgn) are active metabolites of azathioprine (aza) and 6-mercaptopurine (6mp). higher remission rates have been observed in patients with higher 6-tgn levels. however, many physicians prescribe aza/6mp using milligrams per kilogram (mg/kg) dosing regimens