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S12.45 Evidence that the mitochondrial phosphate carrier is a key component of the mitochondrial permeability transition pore

✍ Scribed by Pinadda Varanyuwatana; Anna W.C. Leung; Andrew P. Halestrap


Book ID
119193774
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
66 KB
Volume
1777
Category
Article
ISSN
0005-2728

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## Abstract The pathological consequences of traumatic head injury result largely from the opening of the mitochondrial permeability transition pore (mPTP). The mPTP opens due to a decrease in brain phosphorylation energy resulting in a further decrease in brain ATP production and a measurable incr