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S12: Idiosyncratic hepatotoxicity: Mechanisms and predictability

✍ Scribed by Jack Uetrecht


Book ID
113608003
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
50 KB
Volume
61
Category
Article
ISSN
0940-2993

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The mechanism of cadmium-mediated acute hepatotoxicity has been the subject of numerous investigations and although some uncertainties persist, sufficient evidence has emerged to provide a reasonable account of the toxic process. Acute hepatotoxicity involves two pathways, one for the initial injury